Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Box plot of cycle 3 Ctrough immediately following 4‐, 6‐, and 9‐week delays in dosing in 1000 virtual patients. Patients were given 3 cycles (840 mg, 420 mg, 420 mg) as scheduled. The third cycle was prolonged for a 4‐, 6‐, and 9‐week delay before the next cycle (fourth) was administered. Threshold represents the Ctrough target (20 µg/mL). Ctrough, lowest concentration before the next dose is given.
