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Apparent KD for 18 binding to gp120.[a]
|
Compound |
ka (103)(1/M⋅s) |
kd (10−3)(1/s) |
KD (μM) |
|---|---|---|---|
|
18 |
3.45±0.29 |
2.73±0.23 |
0.80±0.13 |
|
PRM‐A |
1.93±0.42 |
12.64±2.92 |
6.52±0.11 |
[a] Average and standard deviation of kinetic parameters obtained from four replicate SPR experiments measuring the binding response between gp120 and 18/PRM‐A.
