Fig 1.

Overall survival in patients with myelofibrosis according to frailty status (n = 439). (A) Overall survival data, from time of first visit, among 439 patients with myelofibrosis, stratified by the frailty status, defined using a 35‐item cumulative deficit frailty index. The Kaplan–Meier curves shown were adjusted for the multivariable cox proportional regression model in (B). (B) Forest plot represents the HRs from the multivariable cox regression analysis to determine the association between frailty status and overall survival. For all estimates, P ≤ 0·05 was considered statistically significant. ECOG, Eastern Co‐operative Group scale; HCT‐CI, haematopoietic stem cell transplant comorbidity index; DIPSS, Dynamic International Prognostic Scoring System; Int, intermediate; CI, confidence interval; FI, frailty index. [Colour figure can be viewed at wileyonlinelibrary.com]