| Reagent | Amount |
|---|---|
| Hi‐C library on beads (from step 42) | 41 µl |
| 10× NEBuffer 2.1 | 5 µl |
| 10 mM dATP | 1 µl |
| 5 U/µl Klenow fragment (3→5′ exo–) | 3 µl |
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