TABLE 5.
RNA‐seq Expression Data
| Gene | Expression in blood | Locus number | CH p value | CH p corr valuea | M p value |
|---|---|---|---|---|---|
| POLR1B | Yes | 2 | 7.50 × 10−5 | 8.3 × 10−4 | 0.50 |
| TMEM87B | Yes | 2 | 0.014 | 0.15 | 0.45 |
| ZC3H8 | Yes | 2 | 0.084 | 0.92 | ‐ |
| DUSP10 | Yes | 1 | 0.725 | 1 | ‐ |
| MERTK | Yes | 2 | 0.527 | 1 | ‐ |
| TTL | Yes | 2 | 0.465 | 1 | ‐ |
| MMS22L | Yes | 4 | 0.424 | 1 | ‐ |
| FBLN7 | Yes | 2 | 0.361 | 1 | ‐ |
| ZC3H6 | Yes | 2 | 0.285 | 1 | ‐ |
| FTCDNL1 | Yes | 3 | 0.123 | 1 | ‐ |
| UFL1 | Yes | 4 | 0.123 | 1 | ‐ |
| FHL5 | No | 4 | ‐ | ‐ | ‐ |
| FUT9 | No | 4 | ‐ | ‐ | ‐ |
| GPR63 | No | 4 | ‐ | ‐ | ‐ |
| RGPD8 | No | 2 | ‐ | ‐ | ‐ |
| SATB2 | No | 3 | ‐ | ‐ | ‐ |
Genes were selected based in the eQTL mapping in FUMA.22
a
The p values were Bonferroni corrected for 11 tests.
CH = cluster headache; eQTL = expression quantitative trait locus; FUMA = Functional Mapping and Annotation; M = migraine.