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. 2021 Jun 26;60(32):17514–17521. doi: 10.1002/anie.202101864

Figure 2.

Figure 2

Design of MIF targeting PROTACs. Optimal binding poses of MIF with 2 (A, PDB 1GCZ)[28] and 3 (B, PDB 5HVT).[29] MIF is shown as a pale‐green cartoon and the key residues forming the binding pocket are represented as sticks. Docking studies were performed with Discovery Studio and models were prepared with Pymol.