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. 2021 May 25;73(7):1220–1232. doi: 10.1002/art.41652

Figure 2.

Figure 2

CD8+CCR10+ T cells are prototypically DNAM‐1high. A, CD8+CCR10+ T cells coexpressed high levels of DNAX accessory molecule 1 (DNAM‐1). B, Distinct populations of CD8+ T cells were distinguishable based on expression of DNAM‐1 and T cell immunoreceptor with Ig and immunoreceptor tyrosine‐based inhibition motif domains (TIGIT), including DNAM‐1highTIGIT−, DNAM‐1highTIGIT+, and DNAM‐1−TIGIT+. C, The majority of CD8+CCR10+ T cells were either DNAM‐1highTIGIT− or DNAM‐1highTIGIT+. D, Within CD8+CCR10+ T cells with high expression of DNAM‐1, TIGIT coexpression was reduced in patients with psoriatic arthritis (PsA). In C and D, symbols represent individual subjects (healthy controls [HCs] [white symbols], patients with psoriasis [Pso] [gray symbols], and patients with PsA [black symbols]); bars show the median and interquartile range. * = P < 0.05. Color figure can be viewed in the online issue, which is available at http://onlinelibrary.wiley.com/doi/10.1002/art.41652/abstract.