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. 2021 May 25;73(7):1220–1232. doi: 10.1002/art.41652

Figure 3.

Figure 3

Enrichment of CD8+CCR10+ T cells in skin, but not in synovial fluid (SF). A, CD8+CCR10+ T cell frequency in paired nonlesional (NL) skin, lesional (L) skin, and peripheral blood mononuclear cells (PBMCs), and in nonpaired SF mononuclear cells (SFMCs). B–D, Expression of CCR4 (B), cutaneous lymphocyte antigen (CLA) (C), and β7 integrin (D) in CCR10+ versus CD8+CCR10− T cells. E, CD8+CCR10+ T cell frequency in PBMCs from a patient with psoriasis before psoriatic arthritis (PsA) onset and in PBMCs and SFMCs from the same patient at initial PsA onset. F, Frequency of CD8+CCR10+ T cells in paired nonlesional skin, lesional skin, and PBMCs from a patient with PsA. Symbols in A represent individual subjects (patients with psoriasis [Pso] [gray symbols] and patients with PsA (black symbols); bars in A–D show the median and interquartile range. * = P < 0.05. Color figure can be viewed in the online issue, which is available at http://onlinelibrary.wiley.com/doi/10.1002/art.41652/abstract.