Figure 4.

Receiver‐operating‐characteristics curves for prediction of trisomy 21 by least absolute shrinkage and selection operator (LASSO) model and, individually, eight ultrasonographic markers included in LASSO model, in training set (a) and validation set (b). Areas under the curves are given in Table 2. d2, distance between anterior edge of prefrontal skin and mandibulomaxillary line; FMF, frontomaxillary facial angle; FNA, frontonasal facial angle; FPL, facial profile line; MMF, mandibulomaxillary facial angle; MNM, maxilla‐nasion‐mandible angle; NT, nuchal translucency thickness; PT/NBL, prenasal‐thickness‐to‐nasal‐bone‐length ratio.