FIGURE 2.

Circ_GRHPR promotes the proliferation and invasion of non‐small cell lung cancer (NSCLC) cells. (A) qRT‐PCR analysis of circ_GRHPR expression in normal lung epithelial BEAS‐2B cells and NSCLC cells. (B) The transfection efficacy of circ_GRHPR and GRHPR expression in PC‐9 and H1299 cells was detected using qRT‐PCR analysis. (C) The proliferation status of PC‐9 and H1299 cells was determined by RTCA assay. (D) The invasion status of PC‐9 and H1299 cells was determined by transwell assay. (Right) average number of cells in five fields under a 10× microscope. (E) Circ_GRHPR promoted the proliferation of NSCLC cells in nude mice. The three pictures represent solid tumour volume, tumour growth curve, and tumour weight. Data are shown as the mean ± SD, p < 0.05 was considered statistically significant (*p < 0.05/**p < 0.01/***p < 0.001)