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. 2021 Jun 6;302(1):68–85. doi: 10.1111/imr.12985

FIGURE 8.

FIGURE 8

Induction of T cell tolerance by mFbs and mTECs. The immature mFbs give rise to mature mFbs upon interaction with SP thymocytes expressing lymphotoxin (LTα1β2). The mature mFbs promote mTEC development. Both mTECs and mFbs express and present self‐antigens, thus contributing to the deletion of self‐reactive SP thymocytes and the establishment of central tolerance