Table I.
Baseline characteristics and medical history for orofacial granulomatosis patients according to odontogenic infection
| Variable | Total (n = 165) | OFG-N (n = 47) | OFG-I (n = 118) | P value |
|---|---|---|---|---|
| Age at disease onset, y | 49 (5-83) | 39 (5-72) | 51 (20-83) | <.001 |
| Age, y | 51 (5-83)∗ | 41 (5-72)∗ | 53 (23-83) | <.001 |
| Women | 52 (7-83) | 49 (7-72) | 53 (23-83) | |
| Men | 45 (5-77) | 30 (5-63) | 53 (32-77) | |
| Women, No. (%) | 117 (70.9) | 23 (48.9) | 94 (79.7) | <.001 |
| Duration of disease, mo | 12 (1-240) | 10 (2-120) | 12 (1-240) | .32 |
| Medical history, No. (%) | ||||
| Allergy | 32 (19.4) | 9 (19.1) | 23 (19.5) | >.99 |
| Cardiovascular diseases | 45 (27.3) | 8 (17.0) | 37 (31.4) | .04 |
| Digestive system diseases | 15 (9.1) | 4 (8.5) | 11 (9.3) | >.99 |
| Skin diseases | 4 (2.4) | 1 (2.1) | 3 (2.5) | >.99 |
| Endocrine diseases | 3 (1.8) | 1 (2.1) | 2 (1.7) | >.99 |
| Urinary system diseases | 3 (1.8) | 0 | 3 (2.5) | |
| Nervous system disease | 3 (1.8) | 0 | 3 (2.5) | |
| Respiratory disease | 2 (1.2) | 1 (2.1) | 1 (0.8) | .49 |
| Autoimmune diseases | 2 (1.2) | 1 (2.1) | 1 (0.8) | .49 |
| Genital system diseases | 2 (1.2) | 0 | 2 (1.7) | |
| Clinical characteristics of OFG | ||||
| Lip enlargement, No. (%) | .25 | |||
| Upper lip | 44 (26.7) | 15 (31.9) | 29 (24.6) | |
| Lower lip | 73 (44.2) | 16 (34.0) | 57 (48.3) | |
| Both lips | 48 (29.1) | 16 (34.0) | 32 (27.1) | |
| Extent of disease, No. (%) | ||||
| Solely lip manifestation | 57 (34.5) | 33 (70.2) | 24 (20.3) | <.001 |
| Intraoral manifestation | 30 (18.2) | 7 (14.9) | 23 (19.5) | .66 |
| Perioral or facial swelling, erythema | 78 (47.3) | 7 (14.9) | 71 (60.2) | <.001 |
Data are expressed as median (range) unless otherwise indicated.
OFG, Orofacial granulomatosis; OFG-I, orofacial granulomatosis infected; OFG-N, orofacial granulomatosis negative.
∗
Indicates which group has been compared between women and men and that the difference is statistically significant.