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. Author manuscript; available in PMC: 2021 Aug 13.
Published in final edited form as: J Thorac Oncol. 2020 Jun 17;15(10):1599–1610. doi: 10.1016/j.jtho.2020.06.001

Table 4.

Grading Scheme for Invasive Pulmonary Adenocarcinomas

Grade Differentiation Patterns

1 Well-differentiated Lepidic predominant with no or less than 20% of high-grade patterns
2 Moderately differentiated Acinar or papillary predominant with no or less than 20% of high-grade patterns
3 Poorly differentiated Any tumor with 20% or more of high-grade patterns

The model is based on the predominant histologic plus high-grade patterns. The latter includes solid, micropapillary, and complex glandular patterns.