Table VI.
Ophthalmic medication use
| History of atopic dermatitis |
History of asthma only |
All patients |
|
|---|---|---|---|
| n (%) | n (%) | n (%) | |
| Any ophthalmic medication use prior to starting dupilumab | 170 (9.4) | 22 (17.1) | 204 (9.5) |
| Topical antihistamines | 52 (2.9) | 4 (3.1) | 58 (2.7) |
| Topical steroids | 64 (3.5) | 10 (7.8) | 77 (3.6) |
| Topical steroid antibiotics | 25 (1.4) | 2 (1.6) | 31 (1.4) |
| Topical antibiotics | 71 (3.9) | 8 (6.2) | 83 (3.9) |
| Topical NSAIDs | 13 (0.7) | 0 (0) | 14 (0.7) |
| Topical cyclosporine | 11 (0.6) | 1 (0.8) | 13 (0.6) |
| Topical lifitegrast | 7 (0.4) | 1 (0.8) | 9 (0.4) |
| Any ophthalmic medication use after starting dupilumab | 251 (13.8) | 24 (18.6) | 300 (14) |
| Topical antihistamines | 64 (3.5) | 6 (4.7) | 78 (3.6) |
| Topical steroids | 103 (5.7) | 7 (5.4) | 117 (5.5) |
| Topical steroid antibiotics | 67 (3.7) | 4 (3.1) | 78 (3.6) |
| Topical antibiotics | 77 (4.2) | 10 (7.8) | 96 (4.5) |
| Topical NSAIDs | 16 (0.9) | 0 (0) | 17 (0.8) |
| Topical cyclosporine | 18 (1.0) | 2 (1.6) | 21 (1.0) |
| Topical lifitegrast | 12 (0.7) | 2 (1.6) | 16 (0.7) |
| Any ophthalmic medication use after starting dupilumab, among those who developed a new ocular surface disorder diagnosis | 95 (59.7) | 6 (42.9) | 103 (56.9) |
| Topical antihistamines | 23 (14.5) | 1 (7.1) | 25 (13.8) |
| Topical steroids | 43 (27.0) | 0 (0) | 44 (24.3) |
| Topical steroid antibiotics | 28 (17.6) | 1 (7.1) | 30 (16.6) |
| Topical antibiotics | 27 (17.0) | 2 (14.3) | 30 (16.6) |
| Topical NSAIDs | 3 (1.9) | 0 (0) | 3 (1.7) |
| Topical cyclosporine | 9 (5.7) | 0 (0) | 9 (5.0) |
| Topical lifitegrast | 3 (1.9) | 2 (14.3) | 5 (2.8) |
| Any ophthalmic medication use after starting dupilumab, among those who developed a new ocular surface disorder diagnosed by an ophthalmologist | 44 (65.7) | 6 (66.7) | 51 (64.6) |
| Topical antihistamines | 13 (19.4) | 1 (11.1) | 14 (17.7) |
| Topical steroids | 28 (41.8) | 2 (22.2) | 31 (39.2) |
| Topical steroid antibiotics | 13 (19.4) | 1 (11.1) | 14 (17.7) |
| Topical antibiotics | 15 (22.4) | 3 (33.3) | 19 (24.1) |
| Topical NSAIDs | 4 (6.0) | 0 (0) | 4 (5.1) |
| Topical cyclosporine | 5 (7.5) | 0 (0) | 5 (6.3) |
| Topical lifitegrast | 2 (3.0) | 1 (11.1) | 3 (3.8) |
NSAIDs, Nonsteroidal anti-inflammatory drugs.