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. 2021 Aug 2;8(5):e1039. doi: 10.1212/NXI.0000000000001039

Figure 3. Dementia Biomarkers in Patients With Autoimmune Encephalitis.

Figure 3

Dementia CSF biomarkers in 44 patients with autoimmune encephalitis cutoff values to be considered abnormal were (A) t-tau > 400 pg/mL, (B) p-tau > 64 pg/mL, (C) a t-tau/p-tau ratio of >30, (D) Aβ42 < 500 pg/mL, and (E) a t-tau/Aβ42 ratio of >0.52. (F) A positive 14-3-3 is abnormal. Two patients with t-tau values of 14,720 and 2,800 were maximized at 2001. Five patients with a positive 14-3-3 had been tested by RT-QuIC, all negative. Filled diamond symbols represent abnormal results, and half-filled symbols represent normal results. Aβ42 = amyloid-beta-42; CASPR2 = contactin-associated protein-like 2; GABABR = gamma-aminobutyric acid B receptor; LGI1 = leucine-rich glioma-inactivated 1; NMDAR = NMDA receptor; p-tau = phosphorylated tau; RT-QuIC = real‐time quaking-induced conversion; t-tau = total tau.