Figure 3. Significant Laboratory Values Before/During/After COVID-19 Infection.

Laboratory tests were obtained before, during, and after COVID-19 infection. (A) Laboratory values before, during, and after COVID-19 infection grouped by hospitalization status (nonhospitalized [left] and hospitalized [right]) were analyzed for significant effects of time and/or hospitalization. Values are listed as averages with SEM in parenthesis, and the rightward column indicating the number of values included in that average. Values represent unique contributions from 49 nonhospitalized patients and 19 hospitalized patients. Significance was determined by two-way analysis of variance, with significance between each group determined by Bonferroni post hoc analysis. Significant effect of time was found for aspartate transaminase. Significant effect of hospitalization status was found for absolute lymphocyte count, hemoglobin, and albumin. There was a significant interaction between time and hospitalization status for absolute lymphocyte count with post hoc analysis indicating significance during hospitalization. Post hoc analysis did not indicate a significant individual interaction for hemoglobin, aspartate transaminase, or albumin. Significant (p < 0.05) effect of subgroups in post hoc analysis is indicated by *. (B) Absolute lymphocyte count was lower at all time points in the hospitalized group. There were also unique trends in each group, with nonhospitalized patients having a peak during acute infection, whereas hospitalized patients demonstrated a nadir during acute infection. Error bars represent SEM. Significance through Bonferroni post hoc analysis is indicated by *. COVID-19 = coronavirus disease 2019.