Table 1. Demographic and Clinical Characteristics of the Seronegative Population at Baseline.*.
| Characteristic | REGEN-COV (N=753) |
Placebo (N=752) |
Total (N=1505) |
|---|---|---|---|
| Age | |||
| Mean (range) — yr | 43.2 (12–87) | 42.7 (12–92) | 42.9 (12–92) |
| ≥50 yr — no. (%) | 294 (39.0) | 280 (37.2) | 574 (38.1) |
| Male sex — no. (%) | 333 (44.2) | 358 (47.6) | 691 (45.9) |
| Race or ethnic group — no. (%)† | |||
| White race | 653 (86.7) | 635 (84.4) | 1288 (85.6) |
| Black race | 62 (8.2) | 78 (10.4) | 140 (9.3) |
| Asian race | 23 (3.1) | 19 (2.5) | 42 (2.8) |
| American Indian or Alaska Native ethnic group | 3 (0.4) | 4 (0.5) | 7 (0.5) |
| Native Hawaiian or Pacific Islander ethnic group | 1 (0.1) | 2 (0.3) | 3 (0.2) |
| Other‡ | 11 (1.5) | 14 (1.9) | 25 (1.7) |
| Hispanic or Latinx ethnic group — no. (%)† | |||
| Yes | 291 (38.6) | 319 (42.4) | 610 (40.5) |
| No | 459 (61.0) | 428 (56.9) | 887 (58.9) |
| Other§ | 3 (0.4) | 5 (0.7) | 8 (0.5) |
| Mean weight — kg | 81.3±19.9 | 81.2±19.7 | 81.3±19.8 |
| BMI¶ | |||
| Mean | 28.9±12.4 | 28.5±6.3 | 28.7±9.8 |
| ≥30 — no. (%) | 261 (34.7) | 250 (33.2) | 511 (34.0) |
| High risk of Covid-19 — no. (%) | |||
| Any high-risk factor | 238 (31.6) | 221 (29.4) | 459 (30.5) |
| ≥65 yr of age | 76 (10.1) | 55 (7.3) | 131 (8.7) |
| BMI ≥35 | 99 (13.1) | 104 (13.8) | 203 (13.5) |
| Chronic kidney disease | 17 (2.3) | 11 (1.5) | 28 (1.9) |
| Diabetes | 58 (7.7) | 45 (6.0) | 103 (6.8) |
| Immunosuppressive disease | 5 (0.7) | 2 (0.3) | 7 (0.5) |
| Receipt of immunosuppressive therapy | 4 (0.5) | 11 (1.5) | 15 (1.0) |
| ≥55 yr of age with cardiovascular disease, hypertension, or COPD | 99 (13.1) | 90 (12.0) | 189 (12.6) |
| Total no. of households | 679 | 686 | 1209 |
| Household size — no. of participants/total no. of households (%) | |||
| 1 person | 486/679 (71.6) | 503/686 (73.3) | 989/1209 (81.8) |
| 2 persons | 146/679 (21.5) | 136/686 (19.8) | 172/1209 (14.2) |
| 3 persons | 30/679 (4.4) | 30/686 (4.4) | 31/1209 (2.6) |
| 4 persons | 13/679 (1.9) | 13/686 (1.9) | 13/1209 (1.1) |
| >4 persons | 4/679 (0.6) | 4/686 (0.6) | 4/1209 (0.3) |
| Participants with an index patient participating in COV-2067 trial — no. (%) | 187 (24.8) | 186 (24.7) | 373 (24.8) |
*
Plus–minus values are means ±SD. COPD denotes chronic obstructive pulmonary disease, and Covid-19 coronavirus disease 2019.
†
Race and ethnic group were reported by the participants. Data on Hispanic or Latinx ethnic group were collected separately from data on other ethnic groups.
‡
“Other” may include not reported, unknown, or multiple races or ethnic groups.
§
“Other” may include not reported or unknown.
¶
The body-mass index (BMI) is the weight in kilograms divided by the square of the height in meters.