Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 12;10(10):3. doi: 10.1167/tvst.10.10.3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright 2021 The Authors

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

PMC Copyright notice

Figure 3. — Subconjunctival injection of human or rabbit bone marrow MSCs into uninjured rabbit eyes. Human (A) or rabbit (B) bone marrow–derived MSCs were subconjunctivally injected in rabbits at different doses and were followed up to 12 weeks to evaluate the safety. Some rabbit eyes injected with higher doses of human MSCs showed mild redness and swelling in the conjunctival injection area until week 6 (arrows), which resolved by week 12. This pattern was also observed on the first week when rabbit corneas were injected with higher concentration (6 × 10⁶) of rabbit MSCs. In weekly follow-ups, there was no abnormal finding including corneal epithelial defects, corneal neovascularization and haze formation, conjunctival scarring, or any other ocular toxicity in any groups. h-MSC: human MSC; r-MSC: rabbit MSC.