Figure 4.
Efficacy of MSCs in promoting corneal epithelial wound healing in vitro and in vivo. (A) Scratch wounded human corneal epithelial cells were co-cultured with freshly thawed MSCs (i.e., cell culture insert) showing significantly greater wound closure at 18 hours compared with control. (B) The effect of MSCs in vivo after 2-mm central corneal epithelial debridement wounds in mice showing significantly greater wound healing in all the treated eyes compared with control. Error bars: standard deviation. *P < 0.001. Scale bars: 200 µm.