. Author manuscript; available in PMC: 2022 May 1.

Published in final edited form as: Epidemiology. 2021 May 1;32(3):412–420. doi: 10.1097/EDE.0000000000001339

Table 4:

Odds Ratio Estimates of the mediator below the assay limit given the pre-treatment common cause

Mediator	Common cause	OR^a	95% Wald CI^b
On-ART SCA HIV RNA^c below^e	NNRTI-based ART^e	1.9	(0.81,4.5)
on–ART CA HIV RNA^d below^e	NNRTI-based ART^e	0.65	(0.32,1.3)
On-ART SCA HIV RNA^c below^e	Nadir CD4 ≤ 500^e	1.0	(0.43,2.5)
On-ART CA HIV RNA^d below^e	Nadir CD4 ≤ 500^e	0.30	(0.14,0.64)

Odds Ratio.

95% Wald Confidence Interval.

Single-copy plasma HIV RNA, on ART. Analysis restricted to the 94 patients with SCA HIV RNA measured. Without treatment, the probability of on–ART SCA HIV RNA below the assay limit was 60/94, or 64%.

Cell-associated HIV RNA, on ART. All 124 patients had CA HIV RNA measured. Without treatment, the probability of on–ART CA HIV RNA below the assay limit was 52/124, or 42%.

^e:

yes versus no.