Figure 8.

Behavioral alterations in the EPM and social interaction tests in Pcdh19 HET females and their WT littermates. A, B, Total time spent by females in the open arms of the elevated plus maze during the 5 min test at P21 (A) and P60 (B). C, D, Time spent by females interacting with a nonfamiliar female at P21 (C) and P60 (D). The total duration of the test was 5 min. For all panels, the top axis shows the raw data points for each group. To their right, the gap in the line indicates the mean, and the lines extending vertically represent the SD. The group and group sizes are indicated at the bottom. Note that each group appears twice in every graph, but with two different colors. The mean difference for each comparison is plotted in the lower axis as a bootstrap sampling distribution. The black dot represents the mean, and the vertical bar represents the 95% confidence interval. At the top of each graph the significance scores of the one-way ANOVA or Kruskal–Wallis test and their post hoc test are indicated. *p < 0.05; **p < 0.01; ***p < 0.001.