Figure 1.

No effects of sex or estrous cycle on cocaine self-administration. A, Experimental timeline. B, No sex differences were observed for average active hole responding, infusions obtained, or inactive hole responding across the 10 d of cocaine self-administration. C, No sex differences were observed in daily active hole responding, infusions obtained, or inactive hole responding over the 10 d self-administration period. D, No estrous cycle effects were observed for average active hole responding, infusions obtained, or inactive hole responding across the 10 d of cocaine self-administration. Data are shown as the mean ± SEM (n = 36 males; n = 60 females).