Table 2.

Correlation analysis between bacterial genus and PANSS.

Bacteria genus	PANSS
	Positive		Negative		Cognition		Excitement		Depression		Total
	R	P	R	P	R	P	R	P	R	P	R	P
Succinivibrio	0.023	0.857	0.010	0.940	0.061	0.637	0.010	0.939	0.059	0.650	0.027	0.836
Haemophilus	0.189	0.142	0.303*	0.021	0.428**	0.009	0.266*	0.037	0.295*	0.020	0.274*	0.030
Lactobacillus	0.049	0.704	0.042	0.744	0.172	0.182	0.112	0.385	0.070	0.587	0.121	0.347
Megasphaera	−0.139	0.281	0.047	0.718	0.015	0.908	0.113	0.380	0.019	0.886	0.027	0.837
Desulfovibrio	−0.139	0.281	0.045	0.731	0.085	0.511	0.038	0.770	−0.077	0.550	0.017	0.899
Coprococcus	0.027	0.833	−0.285*	0.025	−0.090	0.488	0.069	0.592	−0.039	0.764	−0.135	0.297
Clostridum	0.170	0.186	0.196	0.127	0.186	0.149	0.045	0.731	−0.028	0.828	0.188	0.143
Lachnospira	0.135	0.296	−0.038	0.771	0.039	0.764	0.049	0.705	0.216	0.910	0.039	0.761

Correlation analysis between bacterial genus and PANSS. Bacterial genera were selected from Figure 4 of the heatmap according to the following criteria: taxa that were significantly different from the healthy control group. Among those taxa, succinivibrio, Haemophilus, lactobacillus, megasphaera, desulfovibrio, coprococcus, clostridum, and lachnospira were chosen. Haemophilus is positive associated with psychiatric symptoms on PANSS, Coprococcus is negative associated with negative symptoms on PANSS. PANSS, Positive and negative syndrome scale.

^*P ≤ 0.05,

^**P ≤ 0.001.