Table 1. Evaluation of chemotherapy-induced peripheral neuropathy.
| Factors | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
| Paresthesia | No symptom | Presence of paresthesia and/or decreased DTR (no requirement of medication) | Severe paresthesia (improved with medication, tolerable without medication) | Intolerable paresthesia (intolerable without medication) | Life-threatening consequence: urgent intervention indicated (death related to overdose of medication) |
| Pain | NRS 0 | NRS 1–3 | NRS 4–6 | NRS 7–9 | NRS 10 |
| Motor function | No weakness | Normal ADL | Limiting instrumental ADL and/or light muscle weakness | Limiting self-care ADL and/or marked muscle weakness | Life-threatening consequence: urgent intervention indicated |
ADL, activity of daily living; DTR, deep tendon reflex; NRS, numerical rating scale.