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. 2021 Jun 1;32(5):e73. doi: 10.3802/jgo.2021.32.e73

Table 1. Evaluation of chemotherapy-induced peripheral neuropathy.

Factors Grade 0 Grade 1 Grade 2 Grade 3 Grade 4
Paresthesia No symptom Presence of paresthesia and/or decreased DTR (no requirement of medication) Severe paresthesia (improved with medication, tolerable without medication) Intolerable paresthesia (intolerable without medication) Life-threatening consequence: urgent intervention indicated (death related to overdose of medication)
Pain NRS 0 NRS 1–3 NRS 4–6 NRS 7–9 NRS 10
Motor function No weakness Normal ADL Limiting instrumental ADL and/or light muscle weakness Limiting self-care ADL and/or marked muscle weakness Life-threatening consequence: urgent intervention indicated

ADL, activity of daily living; DTR, deep tendon reflex; NRS, numerical rating scale.