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. 2021 Jul 30;13:657095. doi: 10.3389/fnagi.2021.657095

FIGURE 6.

FIGURE 6

Calcitriol alleviated behavioral and dopaminergic neuron damage in a MPTP model of PD. Schematic diagram of the MPTP model experimental design (A). Performance on the rotarod (B) and pole test (C) (n = 10). TH expression was detected by western blotting in substantia nigra (SN) and striatum (D). TH expression was quantified in SN (E) and striatum (F). Representative images of TH immunofluorescence and immunochemistry of substantia nigra pars compacta [(G), scale bar, 100 μm]. Representative images of TH immunofluorescence and immunochemistry of striatum [(H), upper image scale bar, 100 μm; lower image scale bar, 500 μm]. Data are shown as mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001.