FIGURE 8.

Calcitriol increased VDR and alleviated parthanatos in sections of MPTP models. Representative images of VDR immunofluorescence of substantia nigra [(A), scale bar, 50 μm]. Representative images of cleaved PARP1 immunochemistry of striatum and substantia nigra [(B), scale bar, 50 μm]. Representative images of PAR and AIF immunofluorescence of substantia nigra [(C), scale bar, 20 μm]; then the selected representative magnification images for fluorescence intensity profile analysis of the two channels (AIF and DAPI) (D). The experiments were repeated three times.