TABLE 3.
Cox proportional hazards analysis for MACE.
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95%CI) | p value | HR (95%CI) | p value | |
| Demographic data | ||||
| Age | 1.014 (1.007–1.021) | 0.0002 | 1.008 (1–1.016) | 0.032 |
| Sex | 1.218 (1.03–1.441) | 0.0212 | 1.281 (1.039–1.581) | 0.02 |
| Smoke | 1.092 (0.881–1.353) | 0.4218 | ||
| BMI | 0.982 (0.96–1.004) | 0.1023 | ||
| Comorbidities | ||||
| Arrhythmia | 1.296 (1.056–1.589) | 0.0129 | ||
| Diabetes | 1.345 (1.212–1.492) | 2.54E-08 | 1.44 (1.218–1.704) | 1.94E-05 |
| Heart failure | 1.934 (1.584–2.36) | 8.60E-11 | 1.795 (1.463–2.201) | 1.90E-08 |
| Hypertension | 1.274 (1.108–1.465) | 0.0007 | ||
| Hyperlipidemia | 1.051 (0.855–1.293) | 0.637 | ||
| Medication | ||||
| β-blockers | 0.907 (0.768–1.072) | 0.2519 | ||
| ACEIs | 1.025 (0.893–1.176) | 0.73 | ||
| CCBs | 1.432 (1.245–1.647) | 5.27E-07 | 1.366 (1.152–1.62) | 0.0003 |
| PPIs | 1.207 (1.053–1.384) | 0.0068 | ||
| Biochemical measurements | ||||
| eGFR | 0.998 (0.997–1) | 0.0487 | ||
| ALT | 1.001 (1–1.003) | 0.1452 | ||
| AST | 1.001 (1.001–1.002) | 5.15E-05 | ||
| APOA | 0.532 (0.404–0.699) | 6.09E-06 | ||
| CHOL | 1.032 (0.979–1.089) | 0.2405 | ||
| CK | 1 (1–1) | 6.00E-04 | ||
| CKMB | 1.004 (1.002–1.007) | 4.00E-04 | ||
| GLUC | 1.047 (1.028–1.066) | 1.01E-06 | ||
| HDLC | 0.514 (0.388–0.68) | 3.17E-06 | ||
| LDLC | 1.055 (0.987–1.128) | 0.1144 | ||
| LPa | 1 (1–1.001) | 5.30E-06 | 1 (1–1) | 0.0003 |
| TRIG | 0.991 (0.941–1.042) | 0.7163 | ||
| FT3 | 0.79 (0.71–0.879) | 1.42E-05 | 0.831 (0.735–0.939) | 0.003 |
| FT4 | 1.027 (1.011–1.044) | 0.0009 | ||
| FT3/FT4 | 0.104 (0.0465–0.233) | 3.54E-08 | 0.312 (0.121–0.8) | 0.015 |
| TSH | 0.985 (0.959–1.011) | 0.254 | ||