Table 2.
Clinical Characteristics of Sample
Full Sample
|
CDR=0
|
CDR>0
|
p | ||||
CDR | N | % | N | % | N | % | |
|
|||||||
0 | 27 | 67.5 | 27 | 67.5 | |||
0.5 | 12 | 30.0 | 12 | 30.0 | |||
1 | 1 | 2.5 | 1 | 2.5 | |||
Cognitive | Mean (SD) | Range | Mean (SD) | Range | Mean (SD) | Range | |
|
|||||||
MoCA | 25.20 (2.93) | 20 to 30 | 26.22 (2.67) | 21 to 30 | 23.08 (2.29) | 20 to 28 | 0.001 |
Executive | 0.36 (0.55) | −0.78 to 1.72 | 0.54 (0.52) | −0.56 to 1.72 | 0.00 (0.45) | −0.78 to 1.10 | 0.003 |
Semantic | 1.45 (0.69) | −0.38 to 2.69 | 1.68 (0.60) | 0.37 to 2.69 | 0.96 (0.63) | −0.38 to 2.01 | 0.001 |
Verbal Memory | 0.68 (0.85) | −0.97 to 2.64 | 0.99 (0.69) | −0.78 to 2.64 | 0.03 (0.81) | −0.97 to 1.28 | <0.001 |
Function | |||||||
Communication | 14.53 (3.45) | 2 to 20 | 15.67 (2.53) | 10 to 20 | 12.15 (3.98) | 2 to 17 | 0.002 |
Finances | 17.90 (2.05) | 13 to 20 | 18.33 (1.94) | 13 to 20 | 17.00 (2.04) | 13 to 20 | 0.053 |
Medication Management | 29.97 (4.00) | 19 to 33 | 31.48 (2.39) | 24 to 33 | 26.58 (4.85) | 19 to 33 | <0.001 |
IADLS | 7.95 (0.22) | 7 to 8 | 8.00 (0.00) | 8 to 8 | 7.85 (0.38) | 7 to 8 | 0.037 |
FAQ | 1.41 (2.43) | 0 to 10 | 0.12 (0.44) | 0 to 2 | 4.08 (2.71) | 1 to 10 | <0.001 |
ROI Mean Composite | |||||||
EMF | 0.53 (0.02) | 0.48 to 0.58 | 0.53 (0.02) | 0.49 to 0.57 | 0.53 (0.02) | 0.48 to 0.58 | 0.780 |
LMF | 0.54 (0.03) | 0.49 to 0.59 | 0.55 (0.03) | 0.49 to 0.59 | 0.53 (0.03) | 0.50 to 0.58 | 0.034 |
Note: CDR=Clinical Dementia Rating; MoCA=Montreal Cognitive Assessment; IADLS=Instrumental Activities of Daily Living Scale; FAQ=Functional Activities Questionnaire; ROI=Region of Interest; EMF=Early-Myelinated Fiber composite; LMF=Late-Myelinated Fiber composite
All SENAS scores were presented in unadjusted z-score like units where a score of zero corresponded to the mean of a demographically diverse, non-demented normative sample composed primarily of Hispanics and Whites and differences from the mean were expressed in standard deviation units.