Table 3.
Multivariable analysis of post-progression survival of patients with PTEN-mutant recurrent glioblastoma (rGBM) IDH-WT (N = 70)
Variables | HR (CI 95%) | p-value |
---|---|---|
| ||
Age (years) | 1.00 (0.98–1.03) | 0.778 |
Male | 0.77 (0.42–1.42) | 0.404 |
Preoperative KPS ≥ 80 | 0.59 (0.30–1.17) | 0.130 |
Non-GTR | 1.72 (0.85–3.48) | 0.134 |
Salvage TMZ | 0.84 (0.43–1.65) | 0.610 |
Salvage bevacizumab | 0.91 (0.48–1.73) | 0.775 |
Salvage TTFields | 0.29 (0.12–0.66) | 0.003 |
Significant p-values are bolded
Multivariate analysis was performed using a Cox regression model
TTFields tumor treating fields, KPS Karnofsky Performance Status, GTR Gr oss-total resection TMZ temozolomide, HR hazard ratio, CI confidence interval, WT wildtype