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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: J Neurooncol. 2021 Apr 21;153(1):153–160. doi: 10.1007/s11060-021-03755-1

Table 3.

Multivariable analysis of post-progression survival of patients with PTEN-mutant recurrent glioblastoma (rGBM) IDH-WT (N = 70)

Variables HR (CI 95%) p-value

Age (years) 1.00 (0.98–1.03) 0.778
Male 0.77 (0.42–1.42) 0.404
Preoperative KPS ≥ 80 0.59 (0.30–1.17) 0.130
Non-GTR 1.72 (0.85–3.48) 0.134
Salvage TMZ 0.84 (0.43–1.65) 0.610
Salvage bevacizumab 0.91 (0.48–1.73) 0.775
Salvage TTFields 0.29 (0.12–0.66) 0.003

Significant p-values are bolded

Multivariate analysis was performed using a Cox regression model

TTFields tumor treating fields, KPS Karnofsky Performance Status, GTR Gr oss-total resection TMZ temozolomide, HR hazard ratio, CI confidence interval, WT wildtype