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MTT viability assay of SRF + GA solution and optimized SRF + GA loaded NLC. The SRF + GA loaded NLC shows significant (p < 0.05) cytotoxicity compared to SRF + GA solution after 24 and 48 h. Data are expressed as mean ± SD (n = 6).
| Formulations | IC50 (µg/mL) |
|
|---|---|---|
| 24 h | 48 h | |
| SRF + GA solution | 47.31 | 41.22 |
| SRF + GA loaded NLC | 30.01 | 18.10 |
(SRF; Sorafenib GA; Ganoderic Acid: NLC; Nano lipidic carrier).
