Effects of GBC and GSE on HCT-116 and HT-29 human colorectal cancer cell proliferation. [A]: Concentration-associated effects on HCT-116 and HT-29 cells for 48 h. Cells were treated with 20, 50, 150, 500, and 1000 μg/ml of tested extracts for 48 h. [B]: Time-associated antiproliferative effects on HCT-116 cells. Cells were treated with 50–500 μg/ml of tested extracts for 24, 48, and 72 h. *P<0.05; **P<0.01 vs. control. GBC inhibited cancer cell proliferation in dose- and time-dependent manner. Non-ginsenoside extract GSE increased cell proliferation.