FIGURE 1.

Representative photomicrographs of LATE‐NC and microvascular pathologies. TDP‐43 immunohistochemical staining of amygdala (A), dentate gyrus, hippocampus (B), and middle frontal gyrus (C) indicates the presence of TDP‐43 cytoplasmic inclusions (arrow) with dendritic neurites (arrowhead). H&E staining in the posterior watershed region shows severity of arteriolosclerosis: mild (D), moderate (E), and severe (F). 4G8 immunostaining in the inferior parietal lobule shows severity of amyloid angiopathy: mild (G), moderate (H), and severe (I). Low (J) and high (K) magnification images of a chronic microinfarct in the midfrontal gyrus. Scale bars: 50 µm (A–F), 200 µm (G–J), and 100 µm (K)