TABLE 1.
Basic characteristics of the study participants (n = 749)
| Characteristics | Mean (SD) or N (%) | |
|---|---|---|
| Demographics | ||
| Age at death, mean (SD) years | 90.3 (6.4) | |
| Female, n (%) | 515 (69) | |
| Education, mean (SD) years | 16 (3.5) | |
| Clinical | ||
| AD Dementia, n (%) | 331 (44.2) | |
| aAPOE ε4, n (%) | 186 (25.3) | |
| Vascular and neuropathologic | ||
| AD (NIA‐Reagan), n (%) | 499 (66.6) | |
| LATE‐NC stages, n (%) | ||
| Stage 0 | 340 (45.4) | |
| Stage 1 | 147 (19.6) | |
| Stage 2 | 75 (10) | |
| Stage 3 | 187 (25) | |
| Hippocampal sclerosis | 70 (9.35) | |
| AWS arteriolosclerosise, n (%) | 345 (46.1) | |
| bBG arteriolosclerosise, n (%) | 233 (31.1) | |
| PWS arteriolosclerosise, n (%) | 245 (32.7) | |
| cCAAe, n (%) | 272 (36.5) | |
| dCapillary CAA, n (%) | 94 (12.5) | |
| Chronic microinfarcts, n (%) | 274 (36.6) | |
Abbreviations: PWS, posterior watershed; APOE, apolipoprotein; AWS, anterior watershed; BG, basal ganglia; CAA, cerebral amyloid angiopathy; LATE‐NC, limbic predominant age‐related TDP‐43 encephalopathy neuropathological change.
a
Data missing for 14 participants.
b
Data missing for 1 participant.
c
Data missing for 3 participants.
d
Data missing for 6 participants.
e
Grade of moderate‐to‐severe