Table 1.
Pregnancy outcomes following sublethal LPS challenge in mid and late pregnancy.
| LPS injection | Groups | Exposure (h) | N (Dams) | Early labour % | Fetal death % | Fetal weight (mg) | Placental weight (mg) | F:P ratio |
|---|---|---|---|---|---|---|---|---|
| E15.5 | Control | 4 | 8 | 0 | 10(8/81) | 410 ± 30 | 95 ± 2 | 4.3 ± 0.35 |
| LPS | 8 | 0 | 36(19/53) | 400 ± 30 | 90 ± 3 | 4.3 ± 0.12 | ||
| E14.5 | Control | 24 | 6 | 0 | 3(1/30) | – | – | – |
| LPS | 4 | 0 | 87(20/23) | – | – | – | ||
| E18.5 | Control | 4 | 9 | 0 | 0(0/35) | 1.149 ± 50 | 80 ± 0.9 | 14.16 ± 0.6 |
| LPS | 10 | 0 | 1(1/68) | 1.145 ± 40 | 90* ± 2.0 | 12.80 ± 0.64 | ||
| E17.5 | Control | 24 | 12 | 0 | 2.5(2/80) | 1.130 ± 50 | 82 ± 0.9 | 13.39 ± 0.54 |
| LPS | 22 | 64(14/22) | 2.0(1//51) | 950* ± 60 | 92* ± 3 | 10.72** ± 0.72 |
Statistics: Student’s t-test.
*
p < 0.05;
**
p < 0.01.