Skip to main content
. 2021 Aug 16;131(16):e151002. doi: 10.1172/JCI151002

Figure 1. Model for tumor neoantigen editing via epigenetic modifiers.

Figure 1

Entinostat promotes tumor cells to express neoantigens. Subsequently, T cells recognize tumor neoantigens, expand, and clear tumor cells. Truong et al. showed that, when combined with anti–PD-1 in bladder cancer models, entinostat enhanced antitumor activity (16).