Table 4. PP1 concentration influences ppERK quantity and ultrasensitivity.
The calcium duration producing half-maximal ppERK AUC and the sensitivity to duration were estimated by fitting a hill equation to ppERK AUC vs calcium duration. Values shown are parameter estimates ± standard deviation of the estimate. Width at half max: the calcium duration at half-maximal ppERK.
Pp1 (%) | Width at half max | Hill coefficient |
---|---|---|
10 | 6.0 ± 1.07 | 4.1 ± 1.5 |
18 | 6.7 ± 1.53 | 2.5 ± 1.1 |
50 | 9.9 ± 5.28 | 1.4 ± 1.1 |