Table 2.
Upregulated interferon-stimulated genes
| Gene name | Type I | Type II | Type III |
|---|---|---|---|
| ACCS | X | ||
| APCS | X | ||
| APOBEC3A | X | X | |
| APOBEC3G | X | X | |
| APOL1 | X | X | |
| APOL3 | X | X | |
| CD5L | X | ||
| CFB | X | X | |
| CMPK2 | X | X | |
| CNTRL | X | ||
| CX3CL1 | X | X | |
| CXCL10 | X | X | |
| CXCL11 | X | X | |
| DCK | X | X | |
| DDX58 | X | X | X |
| DDX60 | X | X | |
| DDX60L | X | X | |
| DHX58 | X | X | |
| DNAAF1 | X | ||
| EIF2AK2 | X | X | X |
| EPSTI1 | X | X | X |
| FGL2 | X | X | |
| GBP1 | X | X | X |
| GBP4 | X | X | |
| GBP5 | X | X | |
| GCH1 | X | X | |
| GZMB | X | X | |
| H1FX | X | ||
| HELZ2 | X | X | X |
| HERC5 | X | X | |
| HERC6 | X | X | X |
| HMGB2 | X | ||
| HP | X | X | |
| ICAM1 | X | X | |
| IDO1 | X | X | |
| IFI44 | X | X | |
| IFIH1 | X | X | X |
| IFIT1 | X | X | X |
| IFIT2 | X | X | X |
| IFIT3 | X | X | X |
| IFIT5 | X | X | X |
| IL4I1 | X | X | |
| INO80 | X | ||
| IRF9 | X | X | X |
| ISG15 | X | X | X |
| ISG20 | X | X | |
| KCNAB2 | X | ||
| KRT13 | X | ||
| LCP2 | X | X | |
| LILRA2 | X | X | |
| LILRA5 | X | X | |
| MANEA | X | ||
| MEFV | X | X | |
| MKI67 | X | X | |
| MT2A | X | X | |
| MX1 | X | X | X |
| MX2 | X | X | |
| NADK | X | X | |
| NUB1 | X | X | |
| OAS1 | X | X | X |
| OAS2 | X | X | |
| OAS3 | X | X | X |
| OASL | X | X | X |
| PARP9 | X | X | X |
| PHF1 | X | ||
| PIK3AP1 | X | ||
| PIK3R3 | X | X | |
| PLCD3 | X | ||
| PLEK | X | X | |
| PLEKHO1 | X | ||
| PLSCR1 | X | X | X |
| PRIM1 | X | X | |
| PTMA | X | ||
| PTPN18 | X | ||
| RELB | X | X | |
| RFX5 | X | X | |
| RNF213 | X | X | |
| RRAGC | X | X | |
| RRP1B | X | ||
| RSAD2 | X | X | |
| SAMD9L | X | X | |
| SAMSN1 | X | X | |
| SMCHD1 | X | X | |
| SP110 | X | X | X |
| SPATS2L | X | X | |
| SRSF3 | X | ||
| STAT1 | X | X | X |
| STAT2 | X | X | X |
| TF | X | ||
| TGFB1 | X | ||
| TNFAIP8L2 | X | ||
| TNFSF10 | X | X | |
| UBE2L6 | X | X | X |
| USP18 | X | X | X |
| VWA8 | X | ||
| WARS | X | X | |
| WIPF1 | X | ||
| ZBP1 | X | X |
A list of identified upregulated proteins that are known to be involved in IFN-mediated antiviral signaling (type I, II, or III) as annotated in the Interferome database (47).