Table 4.
Association between lung cancer risk and exposure to organic dust, stratified by history of COPD or asthma
| Exposure to organic dust | Overall | No history of COPD or asthma | With history of COPD or asthma |
|---|---|---|---|
| N=21,655* | N=16,737 | N=4,918 | |
| OR † (95% CI) | OR † (95% CI) | OR † (95% CI) | |
| Never | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
| 1st Quartile | 1.08 (0.98–1.19) | 1.09 (0.86–1.22) | 1.04 (0.85–1.28) |
| 2nd Quartile | 1.12 (1.02–1.23) | 1.06 (0.95–1.18) | 1.32 (1.08–1.62) |
| 3rd Quartile | 1.12 (1.01–1.24) | 1.09 (0.97–1.22) | 1.27 (1.02–1.58) |
| 4th Quartile | 1.32 (1.19–1.46) | 1.27 (1.13–1.42) | 1.49 (1.18–1.87) |
| Test for trend, p-value‡ | <.001 | <.001 | <.001 |
*
Subset of total study population for which information on non-malignant respiratory diseases was available
†
ORs are adjusted for age, sex, study, cigarette pack-years, time-since-quitting smoking, and ever employment in a ‘list A job’
‡
P-values for trend result from logistic regression model with exposure as continuous variable