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Anti-inflammatory and antioxidant properties of HC in HFD-STZ-induced diabetic rats. (a) Fold change of TNF-α, IL-1β, IL-6, iNOS, and COX-2 mRNA level in pancreas tissues of HFD-STZ-treated rats; (b) Serum malondialdehyde (MDA) level; (c) serum nitric oxide. +p < 0.01 and ++p < 0.001 versus normal control group. ∗p < 0.01 and ∗∗p < 0.001 versus HFD-STZ control group. Results are presented as means ± SD (n = 6 each group).
