Table 3.
Levels of FBG, FINS, HOMA-IR, and HbA1c.
| Metabolic parameter | FBG (mg/dl) | FINS (ng/ml) | HOMA-IR | HbA1c (%) |
|---|---|---|---|---|
| Normal control | 97.3 ± 9.0 | 3.2 ± 1.2 | 0.6 ± 0.4 | 7.8 ± 0.7 |
| HFD control | 116.8 ± 5.0 | 3.9 ± 2.5 | 1.1 ± 0.8 | 9.8 ± 0.7 |
| HFD-STZ control | 363.0 ± 21.9++ | 2.8 ± 0.6 | 2.5 ± 0.5+ | 16.7 ± 1.2++ |
| HC (10 mg/kg) | 300.7 ± 6.5∗ | 5.0 ± 2.8 | 3.7 ± 2.0 | 16.3 ± 3.3 |
| HC (100 mg/kg) | 244.3 ± 54.7∗∗ | 3.34 ± 2.7 | 2.0 ± 0.9 | 14.7 ± 2.3 |
| Metformin (100 mg/kg) | 305.2 ± 32.3∗ | 2.8 ± 2.1 | 2.1 ± 1.2 | 16.0 ± 1.3 |
Results are presented as means ± SD (n = 6 each group). +p < 0.05 and ++p < 0.001 versus normal control group. ∗p < 0.05 and ∗∗p < 0.01 versus HFD-STZ control group. FBG: fasting blood glucose; FINS: fasting serum insulin levels; HOMA-IR: homeostasis model assessment of insulin resistance.