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. 2021 Jun 14;27(8):1379–1384. doi: 10.1038/s41591-021-01413-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a, Variant frequencies across the time of the study, including the number of samples collected throughout the study. All values were calculated by averaging over a sliding window of 7 days. All samples sequenced in this study are included herein, including unpaired samples. b, Breakdown of variant frequencies based on the four groups of this study. The pie charts display the proportion of each variant (B.1.1.7, B.1.351 and WT) for paired vaccinated cases versus non-vaccinated controls separated by dosage (as defined in the main text), with cases on the left and their associated control on the right. Only paired samples are shown in the figure.