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. 2021 May 26;27(8):1362–1366. doi: 10.1038/s41591-021-01387-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a, Cyto/chemokine levels were measured using the human immune monitoring 65-plex ProcartaPlex immunoassay in consecutive plasma samples. Samples were measured in duplicates. Data are presented as the log₁₀ of the concentration in pg ml⁻¹. b, Kinetics of S1-reactive and neutralizing antibody responses after BNT162b2. Data are presented as the reciprocal dilution of the last detected sample. IVMP treatment is indicated in red. c, SARS-CoV-2-specific CD4⁺ and CD8⁺ T cell response in exemplary samples after stimulation of PBMCs with spike (S) peptide pool. d, PBMCs were stimulated with S, S1 and S+ peptide pools representing the full length of the spike protein. SEB was used as a positive control. Data are presented as a stimulation index indicating the ratio of the frequency of CD4⁺CD137⁺OX40⁺ or CD8⁺CD137⁺CD69⁺ T cells in the sample and the negative control. SEB, Staphylococcal enterotoxin B.