. Author manuscript; available in PMC: 2022 Sep 1.

Published in final edited form as: Eur J Med Genet. 2021 Jun 20;64(9):104267. doi: 10.1016/j.ejmg.2021.104267

Table 2.

Features selected by the facial analysis technology to identify DS in the DRC population. Horizontal features (H) are normalized to the distance between the lateral canthi. Vertical features (V) are normalized to the distance between the oral commissures and the lateral canthi.

Feature	Normative	DS	p-value
Distance between medial canthi (H)	0.41± 0.03	0.46 ± 0.03	<0.001
Nose length (V)	0.76 ± 0.06	0.65 ± 0.06	<0.001
Philtrum length (V)	0.24 ± 0.04	0.22 ± 0.04	0.023
Average texture at lateral canthi	N/A	N/A	0.0127
Texture at lower border of upper lip	N/A	N/A	0.502