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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Eur J Med Genet. 2021 Jun 20;64(9):104267. doi: 10.1016/j.ejmg.2021.104267

Table 3.

Ranges of the geometric features selected to identify DS in the DRC population compared with the global population and the African descent population. Horizontal features (H) are normalized to the distance between the lateral canthi. Vertical features (V) are normalized to the distance between the oral commissures and the lateral canthi.

Normative Down syndrome
Features DRC African Global DRC African Global
Distance between medial canthi (H) 0.41± 0.03 0.42 ± 0.04 0.41 ± 0.04 0.46 ± 0.03 0.44 ± 0.03 0.44 ± 0.04
Nose length (V) 0.76 ± 0.06 0.79 ± 0.13 0.77 ± 0.12 0.65 ± 0.06 0.69 ± 0.10 0.69 ± 0.11
Philtrum length (V) 0.24 ± 0.04 0.25 ± 0.05 0.26 ± 0.05 0.22 ± 0.04 0.22 ± 0.05 0.24 ± 0.05