Table 4:
Voxel-level coordinates for significant clusters of results for fractional anisotropy (FA) and mean diffusivity (MD)
| DTI metric | Comparison | Regions | Cluster size | T | Coordinates (x, y, z) |
|---|---|---|---|---|---|
|
| |||||
| FA | PSP-RS<controls | Left thalamus/midbrain | 8010 | 8.44 | −1, −7, −9 |
| Left anterior corona radiata | 4869 | 6.28 | −13, 23, 31 | ||
| Right precentral WM | 737 | 6.20 | 57, −1, 16 | ||
| Right cingulum hippocampus | 596 | 6.08 | 16, −34, −10 | ||
| PSP-SL<controls | Right BCC | 71383 | 8.57 | 16, 4, 27 | |
| Left superior frontal WM | 8.29 | −8, −1, 60 | |||
| Left BCC | 7.74 | −18, 3, 29 | |||
| PSP-P<controls | Right fornix/thalamus | 1511 | 6.82 | 2, −6, −7 | |
| PSP-SL<PSP-P | Left BCC | 77529 | 6.40 | −3, 4, 26 | |
| Left superior frontal WM | 6.22 | −12, −1, 55 | |||
| Left BCC | 6.01 | −16, 2, 32 | |||
| PSP-SL<PSP-RS | Left BCC | 46852 | 6.19 | −4, 3, 26 | |
| Right BCC | 6.10 | 7, 1, 26 | |||
| Left superior frontal WM | 5.73 | −9, 0, 59 | |||
|
| |||||
| MD | Controls<PSP-RS | Right thalamus/midbrain | 28010 | 7.98 | 8, −5, −2 |
| Left thalamus/midbrain | 7.63 | −9, −7, −3 | |||
| Left SCP | 7.03 | −6, −32, −20 | |||
| Left superior frontal WM | 704 | 6.40 | −8, −9, 54 | ||
| Right inferior frontal WM | 552 | 6.05 | 47, 17, 19 | ||
| Right precentral WM | 1353 | 5.81 | 10, −20, 63 | ||
| Right BCC | 2118 | 5.49 | 12, 3, 34 | ||
| Controls<PSP-SL | Right precentral WM | 98693 | 9.97 | 42, 0, 43 | |
| Right superior frontal WM | 9.22 | 12, −1, 54 | |||
| Left precentral WM | 9.12 | −48, −4, 38 | |||
| Left posterior limb internal capsule | 855 | 5.62 | −8, −3, −4 | ||
| Right supramarginal WM | 649 | 5.57 | 45, −28, 29 | ||
| Left superior parietal WM | 673 | 5.39 | −22, −50, 53 | ||
| Controls<PSP-P | Right globus pallidus | 629 | 6.26 | 25, −7, −5 | |
| Right thalamus | 2111 | 5.97 | 7, −4, −3 | ||
| PSP-P<PSP-SL | Right superior frontal WM | 10890 | 7.99 | 12, −1, 54 | |
| Right superior frontal WM | 7.84 | 10, 5, 59 | |||
| Right precentral WM | 7.72 | 43, −1, 42 | |||
| Left superior frontal WM | 10234 | 7.14 | −14, 0, 53 | ||
| Left precentral WM | 7.12 | −46, −4, 39 | |||
| Left middle frontal WM | 6.39 | −32, 2, 48 | |||
| PSP-RS<PSP-SL | Right precentral WM | 8811 | 7.99 | 44, −1, 42 | |
| Left precentral WM | 2561 | 7.66 | −47, −4, 38 | ||
| Left superior frontal WM | 2678 | 6.84 | −13, −1, 57 | ||
All clusters that survived cluster-level correction for multiple comparisons (p<0.05) are shown. WM = white matter; BCC = body of the corpus callosum; SCP = superior cerebellar peduncle