Table 5.
Multivariate Cox Model Showing Risk Factors Associated with Cardiovascular Events
| Variables | HR (95%CI) | p |
|---|---|---|
|
| ||
| Age, per 5y increment | 1.16 (1.05–1.27) | 0.003 |
| Stage 1 hypertension at Y1* | 1.19 (1.08–1.30) | 0.007 |
| Stage 2 hypertension at Y1* | 1.27 (1.06–1.48) | 0.01 |
| LV mass index regression, per 5% change | 0.89 (0.84–0.95) | 0.002 |
| LV global longitudinal strain, % | 0.97 (0.93–1.01) | 0.08 |
COA: Coarctation of aorta; LV: Left ventricle; HR: Hazard ratio; CI: Confidence interval
Severity of hypertension at Y1 modeled as categorical variable using the normal/elevated BP group as the reference group.
A diagnosis of hypertension pre-intervention was also independently associated with regression of LVMI (β coefficient ± SE: −0.49±0.23, p0.005). However, we did not input both pre-intervention hypertension and post-intervention hypertension in the same model because of collinearity