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. 2021 Apr 20;51(9):1714–1723. doi: 10.1007/s00247-021-05037-4

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© The Author(s) 2021

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Fig. 3 — Box plots comparing apparent diffusion coefficient (ADC) values at MRI acquired at mid-course of chemotherapy (MRI-2). a−c Box plots compare ADC2 values (a), absolute differential ADC2−ADC1 values (b) and ratio (ADC2−ADC1)/ADC1×100 values (c). Good responders have higher mean ADC values and higher increases in ADC from initial to mid-course MRI than poor responders