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. Author manuscript; available in PMC: 2022 Aug 11.
Published in final edited form as: J Am Chem Soc. 2021 Jul 29;143(31):12294–12303. doi: 10.1021/jacs.1c05550

Figure 5.

Figure 5.

Ntf2-mediated cargo transport through FG-nup gated NanoTraps. (A) Schematics of an NTR-bound cargo (Ntf2-GFP-SNAP-prey, only a monomeric chain of the homodimer is shown) and an NTR-free control molecule (MBP-GFP-SNAP-prey). (B) Permeability of Nsp148 and Nup10048-NanoTraps to the Ntf2-fused molecule (140 kD), compared with the 106 kD NTR-free control. Data are plotted to show mean ± SEM from three trials.