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. 2021 Aug 13;12:4928. doi: 10.1038/s41467-021-25145-x

Fig. 4. MOB1 knockdown protects from β-cell apoptosis in vitro.

Fig. 4

a, b Representative western blots and pooled quantitative densitometry analysis (lower panels) of INS-1E cells transfected with siMOB1 or control siScr and treated with a 22.2 mM glucose or b 22.2 mM glucose plus 0.5 mM palmitate for 48 h (n = 4 independent experiments; n = 3 for clPARP). c Representative western blot and pooled quantitative densitometry analysis (lower panel) of INS-1E cells transfected with siMOB1 or siScr and transduced with Ad-LacZ or Ad-LATS2 for 48 h (n = 3 independent experiments). Results were normalized to the respective control conditions and ratios, in which a normal distribution of results cannot be proven, were analyzed. Data are expressed as means ± SEM. *p < 0.05, **p < 0.01; all by two-tailed Student’s t-tests.