Table 1.
Summary of clinical features of the cognitive impairment disease patients in this study.
| Clinical features | AD (n = 1592) | FTD (n = 110) | DLB (n = 93) | Total (n = 1795) |
|---|---|---|---|---|
| Age at onset, years | 64.7 ± 10.8 | 59.6 ± 11.5 | 65.2 ± 9.9 | 64.5 ± 10.9 |
| Gender (M, %) | 645, 40.4% | 56, 50.9% | 57, 61.3% | 758, 42.1% |
| Age at diagnosis, years | 67.7 ± 10.9 | 62.4 ± 11.8 | 68.0 ± 9.6 | 67.4 ± 11.0 |
| Family history (+, %) | 467, 29.3% | 35, 31.8% | 16, 17.2% | 518, 28.8% |
| Disease duration, years | 3.0 ± 2.4 | 2.8 ± 2.3 | 2.9 ± 2.8 | 3.0 ± 2.4 |
| Education attainment, years | 8.5 ± 4.1 | 9.0 ± 4.0 | 7.7 ± 4.0 | 8.5 ± 4.1 |
| MMSE | 13.8 ± 8.5 | 15.3 ± 9.2 | 15.7 ± 7.7 | 14.0 ± 8.5 |
| APOE genotypes (n, %) | ||||
| APOE4 +/+ | 145, 9.1% | 5, 4.5% | 7, 7.5% | 157, 8.7% |
| APOE4 +/− | 561, 35.2% | 36, 32.7% | 29, 31.2% | 626, 34.9% |
| APOE4 −/− | 886, 55.7% | 69, 62.8% | 57, 61.3% | 1012, 56.4% |
The age at onset, the age at diagnosis, disease duration, educational attainment, MMSE scores are all shown as mean ± standard deviation. Gender, family history, APOE genotypes are all shown as numbers and proportions (%).
AD Alzheimer’s disease, FTD frontotemporal dementia, DLB dementia with Lewy bodies, MMSE Mini-Mental State Examination.